Imetelchat - I like this from the BioPharm Catalyst newsletter six hours.

Re: More JnJ Trouble on The Horizon? by LWS » Thu Apr 04, 2024 4:02 pm. Of course we are anxious: We all believe that the FDA will accept and approve Imetelstat, especially with the EAP in place to cover any time gap between now and approval. Pay special attention to the Final Questions. (RTTNews) - The Canadian market ended modestly higher on Wednesday, led by gains in energy and materials sectors. Check out some Labor Day activities for kids that will keep you active on Labor Day. Nonetheless less, new combinations might be tried or new ways up inhibit telomerase (e. They all serve different purposes like enabling the animal to survive in seawater below freezing point at the South Pole. Well, hence the cytopenias that are "limited and manageable. by biopearl123 » Fri Mar 15, 2024 3:28 pm. We know exactly what will happen. Some as asked for a reckoning of side effects from Imetelstat. With the EAP and compassionate use now a factor, the now fully summitted NDA is likely very close to acceptance and approval, especially considering patients' unmet needs and the uniqueness of this drug. Bridge, thanks for trying to contact me re new Geron patent filing. by lacour_98 » Wed Apr 17, 2024 6:44 pm » in ImetelChat. There is always an infinitesimal chance of rejection, but it is not zero percent. Lane indicated positive results in his recent article. Playboy News: This is the News-site for the company Playboy on Markets Insider Indices Commodities Currencies Stocks. 1/ Ferroptosis (Inflammation in a variety of diseases) 2/ Telomerase & Telomeres. I like this one: “ Imminenter”. A new drug application (NDA) for imetelstat, a telomerase inhibitor used to treat transfusion-dependent anemia in patients with low- to intermediate-1–risk myelodysplastic syndromes (MDS), has been submitted to the FDA, according to a recent press release from Geron Corporation. Even though they may have a unique drug, they chose not to strike at the heart of the king directly. MAIA (THIO) and Geron (Imetelstat) are covering most of the telomerase cancer ongoing opportunities from liqiud to solid. by Ryan » Tue Mar 19, 2024 2:50 pm. by CKTC » Sat Mar 09, 2024 7:03 pm. The PPS will soon be in double digits. Stifel Oncology Forum today very positive (replay now available). Geron is so into inducing, the deduction I make is I too am induced. local scooters for sale by biopearl123 » Tue Feb 27, 2024 9:00 pm. sole dispositive power 0 shares 8. , June 20, 2023--Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today announced the submission to the United States Food and Drug. The modular NDA has been completed, summitted, and has a very, very high probability of being accepted and approved. Once the Public Hearing portion started, I began to make posts (“March 14” thread) as I felt the tide turning. craigslist bronx for sale , (NYSE American: MAIA) (“MAIA,” the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that independent director Mr. Groundhog Day 2024: Punxsutawney Phil did not see shadow. I think we have to remember how COVID dreadfully set back enrollment in many studies. Geron is focused on blood cancers and has not had a chance to think very much about solid tumor cancers. , June 29, 2023-- (BUSINESS WIRE) --Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today announced that an Expanded Access Protocol (EAP) is available for imetelstat, the Company’s first-in-class telomerase inhibitor. snagjob Only a subset of people benefitted. BENEFIT: * A patient who realizes a meaningful improvement in their A) transfusion frequency, B) transfusion …. made an individual purchase of 170,940 shares of the …. , August 21, 2023--Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today announced that the United States Food and Drug Administration (FDA. Great post that sums up the way I feel too. Other salient feature, Grade 3-4 neutropenia in 68 % (manageable and transient) but notably only 1% with febrile neutropenia. He doesn't comment specifically on his experience with Luspatercept, but he was enrolling in the Imetelstat trial in May'23 (~11 months later). by rccola335 » Fri Mar 15, 2024 2:24 pm. If you or anyone you know want their comments considered, there is a time deadline. Feb 5, 2024 · Review Material: SUPPLEMENTARY INFORMATION: Agenda: The meeting presentations will be heard, viewed, captioned, and recorded. If approved, imetelstat will enter an evolving MDS market, with its main rival considered to be Bristol-Myers Squibb's erythroid maturation agent Reblozyl (luspatercept), which was approved to. While I do agree that Imetelchat isn't necessarily the board to discuss the SP and any potential manipulation of the SP, it does and has presented itself here from time to time. Jan 4, 2023 · If approved, imetelstat will enter an evolving MDS market, with its main rival considered to be Bristol-Myers Squibb's erythroid maturation agent Reblozyl (luspatercept), which was approved to. Saturday, December 10, 2022: 2:30 PM. Zeidan at Global Learning Network. by LWS » Thu Mar 14, 2024 8:46 pm. The startup wants to make it easy t. The new drug application for imetelstat is based on findings from the phase 3 IMerge trial, in which the telomerase inhibitor outperformed placebo in the treatment of …. Analysts at Credit Suisse have a price target of $275 on Nvidia, saying its hardware and software give it an edge over rivals in AI. It covered 2 of the indications Imetelstat was currently targeting in its latest Phase 3 Clinical Trials: IMerge - MDS (Myelodysplastic Syndrome) and IMpact – MF (Myelofibrosis), as well as AML (Acute myeloid leukemia); which for all intents and …. In total there are 16 users online :: 0 registered, 0 hidden and 16 guests (based on users active over the past 5 minutes) Most users ever online was 379 on Thu Jul 29, 2021 4:50 am. CHICAGO-- (BUSINESS WIRE) -- MAIA Biotechnology, Inc. It was a bold strategic move and, given the unproven efficacy of imetelstat, the long testing and approval. Advertisement ­Your garage is full of stuff: a workbench, bicycles, an artificial Christmas. I think the after hours volume is more impressive than the price - tomorrow will be interesting. Browse our rankings to partner with award-winning experts that will bring your vision to life. Lisa Meletta - VP, Associate General Counsel, Chief Compliance Officer, Geron Corporation. If my recollection serves, it was around the time of the NEJM Tefferi article. Syros Pharmaceuticals (NASDAQ: SYRS) announced initial data from its Phase 2 SELECT-AML-1 trial evaluating tamibarotene with venetoclax and azacitidine in newly diagnosed, unfit patients with acute myeloid leukemia (AML) and RARA gene overexpression. Just today, Nov 13, 2023, the European Medicines Agency approved a modification to the Imetelstat Paediatric Investigation Plan to allow imetelstat to be administered to children between the ages of 28 days and 18 years with MDS, JMML, …. complex biologics have been gaining in popularity. by biopearl123 » Tue Feb 06, 2024 3:51 pm. Remember, this drug has orphan drug designation and is already approved for a rolling submission. Imetelstat for Diseases other than Cancer. We are committed to creating broader treatment access …. by biopearl123 » Sun Aug 27, 2023 10:31 pm. Housing estates, new highways, and a golf course sit next to one of Africa's largest slums. Bloomberg Philanthropies has honored nine cities for using data to improve their residents' lives, and Los Angeles tops the list. New Comment on Regulatory docket. Please note that the YouTube live video of the meeting will not broadcast until …. I'm seeing new underwriters in TD Cowen and Barclays. It appears however that the placebo group was also subject to these events although not all were cytopenic events. Iron studies, platelets, and white blood cell counts have been within. ----- Two names: John Scarlett & Sergei Gryzanov I don't pretend to understand all of this. This is a follow-up with additional thoughts. All price increases are immediately swatted down. by CKTC » Wed Mar 13, 2024 5:03 pm. (CMG) announced a profit for its fourth quarter that increased from last year but missed the Street estim (RTTNews) - Chipotle Mexican G. Check out the following five most popular ins. What is a safe level? (benefit vs. By using an extensive criterion that includes virtually all adult cardiovascular disorders they want to isolate any potential effect on the QT interval. “To be considered for Priority Review, a drug must address a serious condition and. info Board index ImetelChat; Search; new article. Geron and MAIA are working on cancers, but at the opposite end of the spectrum (blood cancers and single-agents vs. Biopearl Kmall Thanks for all the hard work you've done to keep imetelchat positive, relevant, and fact-based. Lekola, that program is very early and I suspect now Geron will slow roll it and keep the focus on approval for IV Imetelstat. discussions on imetelstat and telomerase. by biopearl123 » Tue Feb 20, 2024 4:09 pm. More specifically; a combination of a telomerase inhibitor and a Bcl-2 inhibitor are useful in treating hematological cancers, including AML. by LWS » Wed Mar 20, 2024 5:39 pm. The distinction between MM, AML, various other hematopoietic disorders is hard enough for us to keep straight, and we work at it almost every day. Prediction: Sometime between today (November 16) and the end of this year (2023) Geron's PPS will be over $4. It's eye-opening to say the least. Stocks are always halted the day of the advisory committee meeting. To this end, the company itself and numerous other sponsors have, for years, been testing ruxolitinib combinations. lyman deerstalker parts Two units every 7-10 days, that’s difficult. Get ratings and reviews for the top 12 gutter guard companies in Maryland City, MD. Claudia B are independently interacting with journalists, who find their discoveries news worthy. My name is Sharon Sams Chandler and I am a 59 year old woman who lives in Roanoke, TX. Even if red flags are raised it's easy to simply disappear. Adding to the discussion of Dr. This is the opening paragraph of a paper by Chandhok and Sekeres in "Leukemia" Feb 15th which I can't copy here sums up the sorry state of affairs in the current treatment of LR/MDS and confirms the absence of data to support improved survival (with current treatment) and the dreadful dependence of patients on blood transfusions. KT --- Imetelchat is a chatroom. Imetelstat is worth quite a bit more than $2. Imetelstat---It all seems to be tied together in one important cancer treatment package, that may lead to cancer cures (TBD by many years of research) --- transfusion independence, disease modification, telomerase, telomeres, ferroptosis, feeling better (fatigue, quality of life, etc. Comments made to the effect that Imetelstat is in a "different space" and the goal is to prolong life and improve the bone marrow picture. by biopearl123 » Tue Nov 28, 2023 4:19 pm. A new drug application (NDA) for imetelstat, a telomerase inhibitor used to treat transfusion-dependent anemia in patients with low- to intermediate-1-risk myelodysplastic syndromes (MDS), has been submitted to the FDA, according to a recent press release from Geron Corporation. info Board index ImetelChat; Search; ASCO Post. Microsoft's popular Windows Live SkyDrive file storage service in the cloud is now available for iOS, allowing users to easily access files in their SkyDrive directly from their iD. Staying in the same job for decades is a thing of the past. From Imetechat - "Go Big Or Go Home - Pt. Re: Hundreds of views every day. Are you curious about compound interest? Learn how it works in relation to investments. 5 days ago · ODAC recommends (12 YES votes from blood cancer experts, 2 No votes) and the FDA approves. Labor Day celebrates hard work and a job well done. I’ll call back the mentions in each of the previous two quarterly calls that Dr. Scarlett has traditionally used the expression, "watch this space" and I always took that to mean, 'watch what we do, not …. However, all agreed that transfusion independence was an important goal. We are committed to creating broader treatment access solutions, and. Last edited by rccola335 on Sun Dec 10, 2023 8:57 pm, edited 1 time in total. This includes paying off any debts that the person owed, and then distributing any remainin. I may be naive but I view the upcoming ADCOM meeting as a positive (the market doesn’t seem to). by LWS » Mon Apr 17, 2023 5:39 pm. Forum: ImetelChat Topic: We are now a little over a month from top line data release Replies: 2 Views: 1448. The biggest negative is likely the $0. This will provide a forum for not only a transparent review of the data, but an opportunity to hear from, well, just about anyone. Two units every 7-10 days, that's difficult. In the past I thought Bridge has made some good points. They've taken an offensive big step in securing a global presence in the space. Re: Down the road, way down the road. made an individual purchase of 170,940 shares of the Company's common stock. I guess it's safe to say around 100 million shares will trade Friday. And of course to John and his team who had the vision to see this through to this point. In certain embodiments, the telomerase inhibitor is imetelstat or imetelstat sodium and the Bcl-2 inhibitor is ABT-199. He is smiling because he knows two prominent things (among the many). More than 30 years after it was first formed, Geron is on the cusp of bringing its first product to market, after imetelstat hit the mark in a phase 3 trial in patients with myelodysplastic. As shareholders let's all hope we get a partnership at some point in the very near future. Are you aware of any agent in development or in the clinic the has resulted in. Abstracts public about a month before. As previously disclosed, in August 2023, Geron Corporation (“Geron” or the “Company”) announced that its New Drug Application (“NDA”) for the. The Insider Trading Activity of YALE PHYLLIS R on Markets Insider. Abstract Approval of new agents to treat higher risk (HR) myelodysplastic syndrome (MDS) has stalled since the approval of DNA methyltransferase inhibitors (DNMTi). Feller was an easy choice to replace Dr. My guesstimate is Geron is at about $1. The alternatives are difficult to find. Helping you find the best gutter guard companies for the job. The discussion has come down to the scheduling of the Oncology ADCOM meeting featuring Imetelstat and John Scarlett's views on the business going forward …. Wholesale Distribution and Parallel Distribution. I think however having some framework that allows evaluation of alternatives help with perspective. Patience is thin, is the understatement of the century. Rizo will keep her unvested stock options going forward. Hi Saltrock and thanks for posting. ImetelChat is a community forum for people who are interested in Imetelstat, a drug candidate for myelofibrosis and other myeloproliferative neoplasms. I didn't realize that even though Imetelstat works better on RS- than RS+, the RS- population outnumber RS+ about 3-1. Bp - Correct, however, pre-market it had traded just under 25million shares, and was up substantially intra-day, like 30-40%. Mistergern, Thanks for the reply. The Applicant is seeking approval of imetelstat (proposed trade name RYTELO) for the treatment of. 149 COMMONWEALTH DRIVE SUITE 2070 MENLO PARK CA 94025 UNITED STATES. The Geron staff (and data) will remind/clarify the meaningful benefits observed within the "non-TI. Furthermore, it's in a separate phase 3 which should produce interim data in early 2024. When a person dies, all of his affairs must be settled through an orderly legal process. 7 Billion since 1997, specific to telomerase drug development, give or take $300 Million. Nov 24, 2022 · Belén Castillo - Clinical Trial Liaison at The Medical Affairs Company (TMAC) for Geron Corporation Barcelona, Spain Aug 2020 - Present 2 yrs 4 mos. While a fairly sizeable amount, it pales in comparison to the approx $200M/yr current burn rate. Cancer Delivery Systems and Artificial Intelligence. Imetelstat is not the "perfect" blood cancer medicine, but it is "very good" in many situations and is needed now by patients and it is unique. PPS to be Determined by NDA Approval by FDA. ODAC has spoken and the FDA always accepts their positive, overwhelmingly good recommendations (12 yes including blood cancer experts, 2 no ). by jayfish101 » Mon Mar 11, 2024 10:10 pm. WEP's management consists of Ex-Big Pharma and Healthcare employees who's former employers include: Sanofi, AstraZeneca, MSD (Merck), Pfizer, Novartis, Alcon, SunGuard, Northgate and Capita. Some Summary Thoughts When I think about summaries 5 names immediately pop up: Dr. Two patients had both post baseline elevated bilirubin > 2 x ULN and ALT≥ 3 x ULN, i. Patnaik’s comments in Lance is just another example to me of the subversive cabal working against Imetelstat commercialization. Geron ( NASDAQ: GERN) is a Nasdaq-listed biotech that has been around a long time - its IPO took place in 1996 at $8 per share, although the company has never won approval for or commercialized a. He is now getting people to read who had never. Negotiated multi-million dollar settlements representing the U. 2024 should be quite the year for us. The company's New Drug Application (NDA) for Imetelstat, specifically for. Fellow Board Members: by biopearl123 » Fri Jun 17, 2022 7:07 pm. They have a lot of power and with that. IMproveMF is a Phase 1 trial designed to identify a safe dosage regimen for the combination of Imetelstat + Ruxolitinib in a frontline MF setting. Morial Convention Center) Claudia Bruedigam, PhD1. by cheng_ho » Thu Feb 29, 2024 2:35 pm. Re: This is a big deal- a convert. Imetelstat's strength, as an important blood cancer medicine, will be in combinations. provided notice in the Federal Register that it has scheduled an advisory committee meeting of the Oncologic Drugs Advisory Committee as part of the NDA. We had the very basics of DNA replication wrong. discuss new drug application (NDA) 217779 for imetelstat for injection, submitted by Geron. I don't see any problem for 6-thio-dG, but would like to hear any ideas on it. Just the newer classification system that up’s more patients out of lower risk categories and highlights that there is utility in more advanced classifications going forward. A first-in-class investigational drug with the potential to extend and enhance lives. How retirement investors can assess the costs of their funds and benefit by choosing the lowest-cost options. Re: The cost to develop a new drug. MAIA Biotechnology Announces Share Purchase by Director Stan Smith, PhD in a $2. While small molecule candidates will probably account for around 50% of the deals, Cantor says. Reblozyl as far as the data up to this point indicates, as well as Imetelstat's potential for commercial market share once approved. by LWS » Mon Mar 04, 2024 11:07 pm. CKTC’s theory about why the FDA came out with guns blazing is interesting. I truly hate to be such a cynical old man in my old age, but investor conferences are nothing more than a dog and pony show for corporate elites to get stroked by a few tea-sipping, coke-snorting bankers to help convince Wall Street to accumulate shares on the cheap and then sell at 5-10% gains weeks later. Imetelstat, a first-in-class telomerase inhibitor, demonstrated meaningful clinical benefit including a robust symptom response rate and potential overall survival benefit in IMbark, a phase II study in intermediate-2 or high-risk myelofibrosis (MF) patients who have relapsed after or are refractory to JAK inhibitors. In the crosshairs of Geron’s development plan was the myelofibrosis market dominated by Incyte’s JAK-2 inhibitor, Jakafi. I can somewhat understand the attack dog mentality of the FDA rep as Imetelstat is a first in class novel drug never before approved for any indication. HEARING IS SCHEDULED IN FRONT OF THE HONORABLE WILLIAM H. Geron says the agency also plans to hold an advisory. With the discussion of Ferroptosis comes the discussion of Imetelstat for diseases other than cancer. Mar 27, 2024 · Re: Take me to your leader. HI, nothing new I have seen from the patient forum area. Cushing's Syndrome (Hypercortisolism) is a rare hormonal disorder caused by over exposure to the hormone, Cortisol. Re: "Next Generation TI Program". Despite recent poorly researched hit articles (be careful where you get your advice, especially here!), 2024 should reveal new AML data, a window into the oral agent development and of course FDA approval. Geron Corporation Message board - Online Community of active, educated investors researching and discussing Geron Corporation Stocks. by LWS » Wed Nov 01, 2023 5:18 pm. It’s a stretch and a guess but regarding the need for hospitalization to manage an adverse effect, that 1% sounds very favorable (if it’s …. 2/ Blood cancers are easier to treat than solid cancers when telomerase inhibitors are the issue. hobby lobby full time hours info Board index ImetelChat; Search; meanwhile, back on topic. I can see a well meaning journalist make an honest mistake. Re: 12-2, take the win right? by LWS » Thu Mar 21, 2024 2:49 pm. I was a little surprised with the timing of the article given the upcoming ASH conference and some of ASH's restrictions and embargos. It is my hope that the flow of accurate, timely and honest information will give patients that are still alive and can benefit from Imetelstat, the hope, and treatment, …. 3 (3)" - June 1, 2020 "In conclusion, from the 3 indications mentioned (MDS, MF, AML) here we can now project anywhere from a $5. info Board index ImetelChat; Search; Geron Announces IMerge Phase 3 Presentations at ASH Highlighting Significant Durability of Transfusion Independence and. I just read the FDA briefing doc and have a lot of questions regarding the data. ImetelChat message board Home Pre-clinical Clinical Commercial Events Contact Clinical research and trials Imetelstat has been evaluated and tested in a variety of clinical trials …. Imetelstat should be in great demand as a proven blood cancer medicine that is needed now (patients, investors, KOLs, potential partners) across the board. Sometimes there will be pre-market and post-market trading. transfusion-dependent anemia in adult patients with low- to intermediate-1 risk myelodysplastic. Please note that the YouTube live video of the meeting will not broadcast until the. by huntingonthebluffs » Sat Apr 06, 2024 8:34 pm » in ImetelChat. Re: A blessing from the hepatologists Major hat tip to Wildrides YMB. Just in from Rockefeller paper, everything we know is wrong. A patient with lower-risk non-del (5q) MDS has been requiring approximately 4 units of RBCs every 4 weeks for the past 6 months. ImetelChat message board Home Pre-clinical Clinical Commercial Events Contact Pre-clinical research There exists a history of preclinical research on telomerase and imetelstat, ignited after the discovery of telomerase by Carol Greider and Elisabeth Blackburn in 1984. by Ryan » Tue Mar 19, 2024 2:58 am. Are you aware of any agent in development or in the clinic that has shown conclusive disease modification in this condition. by Hoosier Investor » Thu Mar 14, 2024 9:49 pm. No shit, you have quite a talent beyond your normal jobs, if those jobs are many. If approved, imetelstat will enter an evolving MDS market, with its main rival considered to be Bristol-Myers Squibb's erythroid maturation agent Reblozyl …. On the Imetelchat front, I would have thought this would be high on the radar, being it’s 10 years in the making to the clinic, not to mention that the patient population is by far the highest among the current diseases being treated in the clinic. It’s not a long read and has several striking quotes. Sergei Gryaznov, now at MAIA)) spent so much time with both companies developing Imetelstat and THIO as important cancer medicines. Jul 24, 2018 · by biopearl123 » Fri Mar 29, 2024 4:50 pm. by biopearl123 » Sun Dec 17, 2023 6:16 pm. Filed after the "to be made public deadline, but will be still considered by ODAC" was a filing from " Institute for Clinical and Economic Review". Points made: that Lus doesn’t seem to promote the malignant clone was viewed as good news. info Board index ImetelChat; Search; Post to Fish Jr. When it happens, Imetelstat becomes a factor in all telomere/telomerase …. by LWS » Wed Apr 17, 2024 7:43 pm. Imetelstat is currently under review for myelodysplastic syndromes (MDS), and the Prescription Drug User Fee Act (PDUFA) date is set for June 16, 2024. I’m seeing new underwriters in TD Cowen and Barclays. He will be starting proton beam …. As someone else previously mentioned, at least the issuance & selling of new …. 0 (new formulations), EAP (ongoing) and NDA approval (coming soon), that Geron is in the driver's seat. I just wanted to be sure Bridge had the opportunity to clarify his comments. Get ratings and reviews for the top 11 gutter companies in Rose Hill, VA. solid cancers and combinations). Volume overload (many patients with MPD. Tefferri and temporally may have been related to the rupture in relationship with Dr. Giving imetelstat in combination with fludarabine and cytarabine may work better in treating patients with refractory or …. #1 take away (beyond transfusion independence) --- "Dynamic Increase of Hemoglobin". Let’s start with the side effects of blood transfusions: 1. Not too much time left in 2023 for JS to make good on two promises. Re: “Next Generation TI Program“. I just wanted to remind folks that the so-called "non-responder" group included 1) Very sick patients coming into the trial with high (>6 units) transfusion burdens. “biopearl, I saw your latest post on Imetalchat regarding EMA and MF approval. It was incredibly heartening and after the first session of “Judge Jury and Executioner” as it seemed to me, I (and everyone including Dr Feller who made sure to make public comment / note to thank the patients who were …. InvestorPlace - Stock Market News, Stock Advice & Trading Tips By buying these best growth stocks of companies exploiting huge, ongoing trends InvestorPlace - Stock Market N. The answer to that question is long and would take up an entire blank page. Re: Finally, disease modification? by Ryan » Mon Mar 11, 2024 7:54 pm. Although some readers may find this topic irrelevant on the Imetelchat board, the fact that the FDA has the ability to stop the deaths of over 300,000 animals per year, mirrors the plight many human patients endure as the FDA keeps Imetelstat from being readily available for those suffering with MDS, MF and AML - in my view. Will you live longer? 2Will you live better? 3. Thanks for the background, pretty impressive advisory board. Jeffrey Savidge mentioned this in his comments to the FDA review: "an ex-marine who courageously put his life on the line fighting for his country in Vietnam and Cambodia. So with those projections in mind, and Anil Kapur's estimates on the number of patients that Imetelstat could treat vs. Or, the thing about good studies. b58 vs vr30 5 years of hard lab work, no vacations and the reward of a discovery of a new pathway!. Feller 1/Imetelstat (for ET) was completely successful with CRs and Cures (all completed by Geron), but that was not sufficiently financially feasible then (at Geron with Dr. CKTC found 2 cases (ODAC recommended, FDA. BP's getting roughed-up and making significant changes in leadership--and profitability outlook--quite early on this year. My comments were based only on not seeing any statement in the FDA material that an additional study was warranted. Expert Advice On Improving Your Home All Projects. minivans for sale in my area This is based upon publications in prestigious medical journals, KOLs, and ASH2023 (December 9-12). by Bigfun » Wed Mar 27, 2024 8:16 pm. by kmall » Tue Oct 10, 2023 3:24 am. Rizo's unenviable position as CMO for Geron. Imetelchat is for Imetelstat and Geron. The Geron staff (and data) will remind/clarify the meaningful benefits observed within the …. Kmall -- This exposure highlights the interest in fighting cancer (remember the Cancer Moonshot). The PM function on chat can be unwieldy. This is a perfect job for Inspector Clouseau. Another way of saying this would be: The data is remarkable (robust and compelling), the NDA is completed and under review, fast-track approvals are assured, and patients' needs have never been greater. The meeting will be open to the public. Helping you find the best gutter companies for the job. Imetelstat, a first-in-class telomerase inhibitor, demonstrated meaningful clinical benefit including a robust symptom response rate and potential overall survival …. The FDA reviews in depth for approval. Perhaps it could be used in true combination, sequentially, or afterwards to help minimize the cancer developing a resistance to the primary chemo treatment. Will your risk of progression to HR or AML be slowed or abolished? Sooner or later there may be a head to head study to look at best first line treatment but not until. The system doesn't allow me to post there anymore so I decided to share my thoughts with you. My thought is that the data is convincing and the EAP (JS said---could be considered a phase 4) is ongoing. S that when the malignant clone which has spawned many many daughter cells that the bone marrow is filled these abnormal cells, bad things happen. Nice, ‘#MDS Gurus from around the world’ pretty much says it all (Quoted the wrong tweet, it was Dr. Geron was betting the farm on imetelstat’s successful challenge to JAK2 inhibitors in the myelofibrosis space. Geron Announces Publication in The Lancet of Results from the IMerge Phase 3 Clinical Trial Evaluating Imetelstat in Lower Risk MDS • Business. Looking at Geron's most recent earnings report, as of June 30, 2023, the company had $400. Patent expiration is looming with several key established drugs in their pipeline. Today, job-hopping has become the new norm resulting in better benefits and a salary increase for Get top content in. The company's New Drug Application (NDA) for Imetelstat, …. Interesting item I excerpted from a continuing education quiz for doctors that I received via Clinical Care Options and Amer Zeidan. There seems to be a 'Geron-factor' (some would say, a 'Geron-curse') with a level of uncertainty that is holding the PPS at these levels. Avalos - VP Trade & Channel Relations - 2022. Scarlett and Geron announced 3 new Clinical Programs (IMproveMF, IMpress, and TELOMERE) and one new Pre-Clinical Program to “explore the use of Imetelstat as a single agent and in combination with current standard of care treatments to expand the potential application of Imetelstat. Geron Corporation (GERN) shares are taking a pay cut of -39. Many things cause cancer if you get too much. by KTArsenal » Thu Feb 08, 2024 11:31 pm » in ImetelChat. Geron aims for FDA approval of imetelstat in June 2024 for hematologic malignancies, targeting an H1 2024 launch. by Hoosier Investor » Fri Dec 22, 2023 3:13 am. They've been direct and forthcoming, and …. Mar 1, 2024 · Luspatercept , as CKTC has pointed out is in the “sweet spot” but pretty soon three questions will be asked of Imetelstat: 1. The concept of a telomerase inhibitor, as an important treatment for most cancers, will have been established in 2024 as a critical breakthrough for the treatment of most. Assistant United States Attorney. Go over to Imetelchat and read Kmall's 6 part series, "Go Big Or Go Home" for a detailed breakdown of patient in …. While my topic may skirt the fringes in some folks opinions here, it is affected by the FDA. info Board index ImetelChat; Search; More Ash 2022 - check out at 6 min 25 sec. The NDA has been summitted, and soon will be accepted and approved. by kmall » Fri Jan 20, 2023 10:02 am. Most small biotechs would probably not announce when they file, only when they were accepted, for fear of subsequent rejection and the loss of face that would inevitably follow. eu is to provide easy access to existing information about imetelstat , its basic workings, clinical potential and results from preclinical and clinical studies. I do expect some significant collaborations or partnerships to accelerate the manufacturing, distribution and sales of Imetelstat. You can be sure that list will include. , January 18, 2024-- (BUSINESS WIRE)--Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today reported that it has granted non-statutory stock options to purchase an aggregate of 895,930 shares of …. There is a lot to be learned here not only in terms of the science of the CD47 pathway, but also in terms of trial design, endpoints, & overall drug development approach. In order to login you must be registered. Patient #9 was put on Luspatercept in Jun'22. Search within: Post subjects and message text. He emphasizes the neutropenia and thrombocytopenia as potential problems. Giving imetelstat in combination with fludarabine and cytarabine may work better in treating patients with refractory or recurrent AML. Will be interesting to see what their analysis reveals. There has been some discussion and concern re grade 3 and 4 events which apparently were reversible and did not result in patient deaths. Jump to When it comes to artificial intelligenc. TJ McLaughlin - Sr Director, Global Pricing and Contracting - 2023. Re: Using fingers to count down now. I like this from the BioPharm Catalyst newsletter six hours ago. Probably should submit to Merriam-Webster for new word of the year. by biopearl123 » Mon Mar 18, 2024 1:13 am. The FDA has a built-in argument against exposing these patients to imetelstat’s side effects without evidence of benefit. 26, 2024) There were no Hy's Law cases. It's a good time to reflect and give THANKS to all of those Clinical Trial patients; past, present and future, who have courageously sacrificed to propel Imetelstat to the brink of approval. His "article" (blog) is nothing but more gaseous click bait. , August 21, 2023--Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today announced that the United States Food and …. Now they look spot on and sagacious. 1 Imetelstat is used to treat patients who are relapsed or refractory to or ineligible for erythropoiesis. by LWS » Fri Dec 22, 2023 4:39 pm. Feb 6, 2024 · They were at the Geron table in 2020 (speculation on my part based on the EA hire from Novartis who returned immediately after meetings with the FDA). Monitoring the health of one's heart and cardiovascular system is one of the most important preventative steps an individual can take to ensure their long-term health. Subforums are searched automatically if you do not disable “search subforums“ below. Former employers: Ipsen, Amgen, Roche, Bristol-Meyers Squibb, Organogenesis. And Geron should, or another company will. ODAC has recommended Imetelstat (March 14th) and the FDA always accepts overwhelmingly positive votes (12 YES votes from blood cancer oncologists, 2 NO votes from others). targets this year, while synthetic lethality and …. Al seleccionar español, usted acepta que solamente partes de la interfaz del sitio actualmente están traducidas. However, I have little doubt that while we wait for marketing authorization, and perhaps even as Revenue begins, our ‘wait’ as investors will involve days and weeks of “max pain”. You agree that “ImetelChat” have the right to remove, edit, move or close any topic at any time should we see fit. Form 8-K - Current report • Edgar (US Regulatory) • 12/15/2023 09:23:51 PM. Apr 4, 2024 · Re: More JnJ Trouble on The Horizon? by LWS » Thu Apr 04, 2024 4:02 pm. Imetelchat, for me, has been a wonderful, educational tool to learn about the process of CTs, how to understand many CT data, and the inner-workings of a biotech business. by biopearl123 » Tue Jan 30, 2024 5:36 am. Inside the pouch is a metal disk that crystallizes the liquid causing it to heat up. 3) Patients who realized a meaningful increase in their hemoglobin levels. Off-label uses will come into focus. Before Imetelstat needless to say, amazing story. 2 billion in assets under management. Acknowledge 50% enrollment in MF study and 2. php?f=1&t=690#p1818 FDA Thoughts on Accelerated Approval Wed Jul 18, 2018 7:34 pm. The Udemy offering comes in the wake of the successful Duolingo IPO earlier this year. Just the newer classification system that up's more patients out of lower risk categories and highlights that there is utility in more advanced classifications going forward. by biopearl123 » Wed Dec 06, 2023 4:02 pm. risk again) New, more sensitive sensors are always being invented. I believe they are focusing on a combination for non-small-cell lung cancer with Regeneron. It was the result of an overly exuberant statement by Dr. So wonderful to see Claudia’s youthful crackling intelligence and enthusiasm and Steven’s gravitas. Importantly, 61 of these are currently in the regulatory phase, pending decisions from the FDA. by LWS » Fri Dec 01, 2023 7:22 pm. Abbvie's CEO Richard Gonzalez is being replaced come summer of this year. by LWS » Sun Jan 28, 2024 6:46 pm. Is it possible that at some point with a significant patient. Syros Pharmaceuticals (NASDAQ: SYRS) announced initial data from its Phase 2 SELECT-AML-1 trial evaluating tamibarotene with venetoclax and azacitidine in newly diagnosed, unfit patients with acute myeloid leukemia (AML) …. made an individual purchase of 170,940 shares of the Company’s common stock. Geron Announces IMerge Phase 3 Presentations at ASH Highlighting Significant …. Then off-label uses can be explored including new combinations. 69% from the low figure of 52 weeks. The board administrator may also grant additional permissions to registered users. The LA-based venture firm that Brendan Wallace and Brad Greiwe launched less than seven years ago already has $3. This company has a fast track and orphan status designation in the US and in Europe. Wish they could be here to help us celebrate. Imetelstat is a novel, first-in-class telomerase inhibitor exclusively owned by Geron and being developed in hematologic malignancies. Imetelstat kills cancer stem-cells in 2 ways and is needed now by suffering patients. by Ryan » Thu Apr 11, 2024 6:17 am. Expert Advice On Improving Your Ho. by LWS » Wed Feb 22, 2023 4:26 am. Geron has Imetelstat with excellent phase 3 trials, a good safety record, disease modification, transfusion improvements, much better survival time, observed CRs and PRs, and unmet patients' needs. It basically means they get down to business. bp & Kmall & others--- It appears that we all agree that Imetelstat has 'crossed all of the medical hurdles and tests' to transition from the EPA (in place) to the NDA approved. Probably looking at a five year timeline (at least) for development and moving through all phases of required study. This is my way of chatting with summaries, updates, new findings and what I believe to be conclusive evidence of Imetelstat's value in a variety of blood cancers now (single-agent) and in various combinations going forward. As a matter of fact, I believe he said that Imetelstat has the potential to treat up to 3x as many patients. Gryzanov invented Imetelchat at Geron and a variation (THIO) at MAIA, where he is now. 302 273 1156 This data is important for some obvious & non-obvious reasons, and I'm optimistic they'll be able to identify a protocol involving the combination of TI + JAK inhibitors. QT interval disorders and specifically "Torsades de Pointes" are of particular interest to EPs. My name is Sharon Sams Chandler and I am a 59 year old woman who lives …. Thanks for posting Jayfish, considering we have heard plenty from KOLs already, virtually all of which has been positive, I think an ADCOM is a positive event and will give voice to patient advocates, patients and physicians. purdue admissions decision I'll call back the mentions in each of the previous two quarterly calls that Dr. Re: Executive Incentives (NDA Submission & FDA Approval) by Hoosier Investor » Mon Feb 13, 2023 1:06 am. In the crosshairs of Geron's development plan was the myelofibrosis market dominated by Incyte's JAK-2 inhibitor, Jakafi. HI & Bp - was able to pull up two topics of interest with regards to the possible EMA "supply chain" question posed by Hoosier, although neither one seems overly pertinent to Geron's current situation focusing on pre-Regulatory submissions. 24 million+ (edited from 30 Million, I overestimated) shares traded here say it's a spring, or a slinkie. There are many other considerations now. 24 million+ (edited from 30 Million, I overestimated) shares traded here say it’s a spring, or a slinkie. , (NYSE American: MAIA) ("MAIA," the "Company"), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that independent director Mr. Compare our services to get started. I would suggest you requesting Bp personally to have your post in this thread removed. Bill Salas - Regional Business Director Southeast, Geron Corporation. Let's hope we all " ride into the sunset" soon as he mentioned. The SAVERS acronymn reminds us of six habits or rituals that can improve our morning routines. by LWS » Fri Jan 26, 2024 5:45 pm. As I recall the end point was ORR. With the recent $43B acquisition of Seagen, Pfizer is poised to be one of the leading Pharmaceuticals targeting oncology in the very near future. I believe we are close to $4 PPS, and moving higher. Geron was betting the farm on imetelstat's successful challenge to JAK2 inhibitors in the myelofibrosis space. It's pretty obvious that the extraordinary manipulation we have seen, not only recently but over the years is in play on some level. If I recall, it had settled up about 10% or so by EOD trading, but that day just goes to show anyone who doubts how fast this can move on momentum, that they should be prepared in the event of a replay. backpage milwaukee alligator These investment firms are willing to pay $3 when they could have literally paid $1's last week in the open. January 2024 -- From Geron 1/Geron is On Target for a Successful Transition to Commercial Company in 2024. Geron aims for FDA approval of imetelstat in June 2024 for hematologic malignancies, targeting an H1 2024 …. There are several types of partnership arrangements. Fish Jr, Biopearl, kmall, and …. MA should be highly likely bolstered by virtually every expert we have heard who makes a point of emphasizing that the grade 3. We made it over the finish line. These colors are caused by different proteins and pigments found in the blood. RC, yes, this one is worth a careful listen even though it is very short. Imetelstat should be in great demand as a proven blood cancer medicine that is needed now (patients, investors, KOLs, potential partners) across the …. in False Claims Act investigations. For Geron, with several partners in. I just wanted to highlight the great preparation, composure, and representation by Faye and team. Recipient: Administrator Your email address: Your name: Subject: Message body: This message will be sent as plain text, do not include any HTML or BBCode. FYI for this October event, doubtful we’ll have the ability to view, or receive any video, transcript or notes for the meeting. Increased Offer! Hilton No Annual Fee 70K + Free Night Cert Offer! American Airlines and the Anguilla Tourist Board have announced that starting April 2, 2022, the carrier will beg. Imetelstat, our novel investigational telomerase inhibitor, binds to telomerase and inhibits its activity, selectively killing the malignant stem and progenitor cells in the bone marrow that are the source of disease in blood cancers, such as myelodysplastic syndromes (MDS) and myelofibrosis (MF). NO ONE can find an ODAC (Oncology Data Advisory Committee) positive recommendation (March 14th) that has ever been rejected by the FDA. why do I feel like there was a lot of manipulation today that benefited certain people. by rccola335 » Sun Apr 21, 2024 1:35 am. KT - McDonald is on the BOD, not an employee, so he isn't sucking as much off the company coffers as a few others whose positions seem questionable at best. I also became a patron of imetelchat. Jose 8m ago "It is very frustrating to witness the constant selling pressure in Geron stock. Fish Jr, Biopearl, kmall, and every member who has lent their voice to our community, your contributions have not gone unnoticed. The real challenge for Geron with the FDA has been going on behind closed doors, and that's the wording of imetelstat's labeling. vta craigslist Go over to Imetelchat and read Kmall's 6 part series, "Go Big Or Go Home" for a detailed breakdown of patient in-discrepancies and market potential with actual links provided of data compiled. through an online teleconferencing and/or video conferencing platform. She was taking blood transfusions on a ~biweekly basis prior to Imetelstat treatment. Mayo’s “tantamount to a cure” language is misleading and largely incorrect. I don't believe that there has ever been any deviation from that pattern. Re: A note from your board moderator. And to all who have contributed to making this board worthwhile. That seems to have everyone on edge, along with the PPS under $3. Aug 27, 2023 · Open Public Hearings (FDA) Thanks bp--- It appears that we will have ample opportunity to interact with the FDA concerning their obligation to approve the NDA for patients' unmet blood cancer needs in a timely way. The FDA has a built-in argument against exposing these patients to imetelstat's side effects without evidence of benefit. modded 328i Imetelstat is an inch from being an approved medicine by the FDA and others. by biopearl123 » Fri May 26, 2023 2:32 am. January 19, 2021 - Imetelstat exhibited dose-dependent inhibition of the telomerase target, as evaluated by reductions in telomerase activity, human reverse transcriptase levels, …. usaasc The science just changed, we didn't understand telomere replication. We know enrollment was at 50% in November. by biopearl123 » Thu Dec 28, 2023 7:19 pm. March 14, 2024 Meeting of the Oncologic Drugs Advisory Committee (ODAC) Webcast Information The Center for Drug Evaluation and Research (CDER) plans to hold the March 14, 2024, meeting of the Oncologic Drugs Advisory Committee virtually via YouTube platform. Good studies have an objective panel of caretakers charged with periodic reviews of the data know as the data and safety monitoring board (DSMB or some other similar name). I don't have any further details other than the link I provided in the 3rd post of this topic chain which opens the official EMA document which sanctions and approves the investigatory use of Imetelstat in children between the ages of 28 days and 18 years with MDS, JMML, and AML. Wow, when somebody writes "my life depends on it", it gives you pause and makes you realize the gravity of this decision. Forum rules - Comments must be civil and on topic. After digging into the Rent the Runway IPO filing this morning, we’re turning to Udemy. This will be of interest to potential partners and collaborators. Acceptance and approval of the Imetelstat NDA is the focus by patients, caregivers and investors. Ignore the noise, only truthful testimonials like this are important now. Doing so may lead to you being immediately and permanently banned, with notification of your Internet Service Provider if deemed required by us. We may be compensated when you click on. Username: Password: I forgot my password. The first patient (1/45) was dosed in June and the trial was ~50% enrolled a couple months ago, and the recent Dr. I would add the list one more question. Review Material: SUPPLEMENTARY INFORMATION: Agenda: The meeting presentations will be heard, viewed, captioned, and recorded. Joined: Thu Jul 14, 2016 2:00 am. Update for TMAC recruitment of P3 IMpact in Europe 1/27/2023: Italy-Arcispedale S Maria Nuova, AO di Reggio Emilia - Reggio Calabria, Italy, 42123 - Now Recruiting. , June 29, 2023--Geron Corporation (Nasdaq: GERN), a late-stage clinical biopharmaceutical company, today announced that an Expanded Access …. RC either we are missing something or the FDA is. I think we'll see an early readout on the Investigator led IMPress HR-MDS/AML trial before we hear anything on Imet 2. Instead by garnering second line approval which seems highly likely, their. Comments submitted before Feb 29th will be presented to the committee. In combinations (research for many years to. It’s very slow moving in case you haven’t noticed. This was equivalent to a total of around 104,000 people*, and is below the ceiling for orphan designation, which is 5 people in 10,000. Previous for reference: Imetelstat is a miracle blood cancer medicine that uniquely modifies that group of diseases, kills cancer stem cells (in 2 ways), brings about transfusion independence, and will effectively treat (PRs, CRs, possible cures) some cancers in combinations. CKTC's theory about why the FDA came out with guns blazing is interesting. Luke Lango Issues Dire Warning A $15. Today the EMA Approves Modification to Imetelstat PIP. Scarlett and Geron announced 3 new Clinical Programs (IMproveMF, IMpress, and TELOMERE) and one new Pre-Clinical Program to "explore the use of Imetelstat as a single agent and in combination with current standard of care treatments to expand the potential application of Imetelstat. Hy’s Law criteria were not met because both patients had more likely alternative causes for the. 18 million in consulting fees to more than two-thirds of the doctors. (B) ADDRESS OF ISSUER`S PRINCIPAL EXECUTIVE OFFICES. There has been considerable discussions (some on this board) about Imetelstat and cancer vaccines. Imetelstat--safe, unique, effective. A textbook example of how to anticipate, prepare, and deliver under …. 5 million, while general and administrative. by rccola335 » Wed Jan 17, 2024 3:52 pm. Speaker #3 was a patient from TX, who said she was ready to meet the Lord upon hearing her treatments were not working. Has anyone seen any comments besides the X comments kindly referenced by RC? Usually there is a bunch of video interviews, articles post ASH. It has been suggested that, because of Imetelstat's huge potential in combinations, oral forms (aspirin like preventative), IMET2. Kenya, the largest economy in East Africa, has some of the starkest inequality in the re. Mar 1, 2024 · Namebackwards could've been writing on Twitter and imetelchat from a local library or somewhere else with a common IP address. Imetelstat is a first-in class telomerase inhibitor for the treatment of transfusion-dependent anemia in patients with lower-risk myelodysplastic syndromes (MDS). We did see a KOL lecturer make general mention of an April date for ADCOM but I have seen nothing concrete. The fight to white out the black box. The bank sees assets such as antibody drug. With all of the handcuffs placed on docs these days (read "you need prior authorization for that") the fight to let doctors be doctors is valid and valuable. Can ASH oral and poster sessions later this week present any new data/information on IMerge trial in addition to the Lancet publication. You agree that "ImetelChat" have the right to remove, edit, move or close any topic at any time should we see fit. Meet Detail, a new startup working on an app for iOS and macOS so that you can turn your iPhone into a software-optimized camera for live video. ), living longer, minimal side effects, combinations. This was equivalent to a total of around 104,000 people*, and is below the ceiling for orphan designation, which is 5 …. Last post by huntingonthebluffs. Filed after the “to be made public deadline, but will be still considered by ODAC” was a filing from “ Institute for Clinical and Economic Review”. While this information will not be disclosed to any third party without your consent, neither "ImetelChat" nor phpBB shall be held. For more information, visit www. I'm also not aware if we're somewhat …. The IP address of all posts are recorded to aid in enforcing these conditions. With all of the handcuffs placed on docs these days (read “you need prior authorization for that”) the fight to let doctors be doctors is valid and valuable. walmart pharmacy ben white erythropoiesis stimulating agents (ESA). Good presentation with Imet highlights. by Ryan » Thu Apr 11, 2024 6:25 am. The way you start your morning can make or break the rest of your day. 1549 Topics 6760 Posts Last post Re: PPS by LWS View the latest post Sat Apr 20, 2024 4:03 pm Login • Register Username: Password: I forgot my password. Part 1 (Imetelstat as a medicine) --- Imetelstat appears to be a great medicine without competition (transfusion independence, survival time, safety, kills cancer cells, potential in combinations, etc. provided notice in the Federal Register that it has scheduled an advisory committee meeting of the Oncologic Drugs Advisory Committee as part of …. Scarlett said they wouldn't be "pinching pennies" to bring Imetelstat to market, he certainly wasn't kidding around. Rizo, it's COMPLETELY apparent that Dr. Geron has always had a strategy. The BMJ analysis also found that industry paid nearly $1. In combinations (research for many …. Geron has added (at expense) many layers of experts including those who specialize in being sure all the FDA t’s are crossed and i’s dotted. It did cross my mind that the delay here could be tied to an early approval on AML since it's mentioned with MDS by both Regulatory Agencies. The End Game: The NDA has been summitted to the FDA, with all (i's) dotted and (t's) crossed. Lab tests can show if you have it. Feb 23, 2022 · GERN has a market cap of $334mn and a cash reserve of $215mn. The FDA, other biotechs, Big Pharma, medical and scientific advancements all fall under that umbrella. These investment firms are willing to pay $3 when they could have literally paid $1’s last week …. 3 days ago · Ryan, you are always teaching me new words. Our KOL's have met this head on and reassured that they have plenty of experience handling these issues and of course they do as Dr. Belén Castillo - Clinical Trial Liaison at The Medical Affairs Company (TMAC) for Geron Corporation Barcelona, Spain Aug 2020 - Present 2 yrs 4 mos. by LWS » Wed Sep 20, 2023 12:41 am. Jun 2015 - Jun 2019 4 yrs 1 mo. bp, Ryan --- The count is now 10 (ODAC Imetelstat meeting, March 14th) Most on this board follow the science, publications, conferences and medical successes of Imetelstat (earth 1), that judge Imetelstat to be a much needed and deeply researched blood cancer medicine. 6 Billion or more annual Global market. Chemotherapy drugs, such as fludarabine and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. by Hoosier Investor » Tue Mar 12, 2024 6:02 pm. It's very slow moving in case you haven't noticed. As I understand it, off-label uses are a 'go' in almost any way the doctor wants to use a medicine once it is approved by the FDA. Feller was a rock star at the ODAC meeting. Let's start with the side effects of blood transfusions: 1. by LWS » Wed Mar 27, 2024 12:08 am. Investment and Insurance Products …. Groundhog Day 2024: Punxsutawney Phil did not see shadow, predicts early spring. Additional Thoughts (Wizard --- YMB (6/15)) Investor conference was interesting. Heating pads are made of a plastic pouch and a clear liquid. Nov 3, 2022 · Speaking of Anil Kapur, I think he quickly put to rest any concerns over Imetelstat vs. watching the webcast today I feel even more strongly that they are trying to hold off as long as possible on a european partner - I feel they are hoping to sell without the complication of having a european partner - the interim analysis for MF will be the first half of 2025 as will the. But during the actual meeting, the stock will be halted. Hide my online status this session. Forum rules - Comments must be civil and on topic - Back up claims with evidence/reasoning/sources (posting links is allowed).